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National Institute of Allergy and Infectious Diseases

 

HIV Therapy for Breastfeeding Mothers Can Virtually Eliminate Transmission to Babies

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HIV Therapy for Breastfeeding Mothers Can Virtually Eliminate Transmission to Babies For HIV-infected mothers whose immune system is in good health, taking a three-drug antiretroviral regimen during breastfeeding essentially eliminates HIV transmission by breast milk to their infants, according to results from a large clinical trial conducted in sub-Saharan Africa and India. These findings from…

Vaginal Ring May Cut HIV Infection Risk if Used Consistently

Vaginal ring - cropped July 2016

NIH Clinical Trial Will Clarify Relationship between Ring Adherence, HIV Infection Risk A new exploratory analysis of data from the ASPIRE study has found that using a drug-infused vaginal ring most or all of the time reduced the risk of HIV infection in women by at least 56 percent. This finding is being reported today…

NIH Expands Investment in HIV Cure Research

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Six Research Teams to Lead Collaborative Investigations Worldwide The National Institutes of Health has awarded approximately $30 million in annual funding over the next five years to six research collaborations working to advance basic medical science toward an HIV cure. The awards comprise the second iteration of the Martin Delaney Collaboratory: Towards an HIV-1 Cure…

NIH Statement on HIV Vaccine Awareness Day

HIV Vaccine Day 2016 - Fauci quote - cropped May2016

Advances in HIV/AIDS research have given us the opportunity to transform the lives of those living with HIV while providing highly effective methods of preventing the infection. This progress has strengthened optimism for achieving a durable end to the HIV/AIDS pandemic. With an estimated two million new HIV infections occurring worldwide annually, however, controlling and…

NIAID to Fund Further Study of Dapivirine Vaginal Ring for HIV Prevention Investment in HOPE Trial Augments Development of Next-Generation Prevention Tools

NIAID image - vaginal ring - ASPIRE study

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today that it would move forward with an open-label extension study of an HIV prevention tool for women: a silicone ring that continuously releases the experimental antiretroviral drug dapivirine in the vagina. The new study builds on…

NIH-Funded Study Finds Critical Population Adheres to PrEP with Coordinated Care

blackmsm

New findings suggest that black men who have sex with men (BMSM) with access to a novel coordinated care program can adhere to pre-exposure prophylaxis (PrEP), a medication regimen that helps prevent HIV infection in uninfected individuals. Researchers reported their results today at a press conference at the Conference on Retroviruses and Opportunistic Infections (CROI)…

Vaginal Ring Provides Partial Protection from HIV in Large Multinational Trial

Woman holding the dapivirine vaginal ring tested in the NIH-funded ASPIRE study.
Credit: International Partnership for Microbicides

NIH-Funded Study Finds Protective Effect Strongest in Women over Age 25 A ring that continuously releases an experimental antiretroviral drug in the vagina safely provided a modest level of protection against HIV infection in women, a large clinical trial in four sub-Saharan African countries has found. The ring reduced the risk of HIV infection by…

The Path to a Cure for Hepatitis C in People with HIV

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Hepatitis C can be a chronic condition that leads to liver failure, and treatments often haven’t worked for patients who are also co-infected with HIV. Thanks to research led by the National Institute of Allergy and Infectious Diseases and Gilead Sciences, new therapies are now available that can cure even complicated cases of hepatitis C…