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NIAID to Fund Further Study of Dapivirine Vaginal Ring for HIV Prevention Investment in HOPE Trial Augments Development of Next-Generation Prevention Tools

NIAID image - vaginal ring - ASPIRE study

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today that it would move forward with an open-label extension study of an HIV prevention tool for women: a silicone ring that continuously releases the experimental antiretroviral drug dapivirine in the vagina. The new study builds on…

Vaginal Ring Provides Partial Protection from HIV in Large Multinational Trial

Woman holding the dapivirine vaginal ring tested in the NIH-funded ASPIRE study.
Credit: International Partnership for Microbicides

NIH-Funded Study Finds Protective Effect Strongest in Women over Age 25 A ring that continuously releases an experimental antiretroviral drug in the vagina safely provided a modest level of protection against HIV infection in women, a large clinical trial in four sub-Saharan African countries has found. The ring reduced the risk of HIV infection by…

NIH Image Gallery Now on Flickr

NIH Image Gallery

Editor’s Note: Our first new media blog of 2015 emphasized the value of “keeping it visual.” So for our final new media post for the year, we share with you an image gallery from the National Institutes of Health that can help enhance your digital content. Looking for health or science related images? The National Institutes…

Early Antiretroviral Therapy Prevents Non-Aids Outcomes in HIV-Infected People, NIH-Supported Study Finds

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New Findings Illustrate Manifold Benefit of Therapy Starting antiretroviral therapy early not only prevents serious AIDS-related diseases, but also prevents the onset of cancer, cardiovascular disease, and other non-AIDS-related diseases in HIV-infected people, according to a new analysis of data from the Strategic Timing of AntiRetroviral Treatment (START) study, the first large-scale randomized clinical trial to…

Starting antiretroviral treatment early improves outcomes for HIV-infected individuals

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For Immediate Release: Wednesday, May 27, 2015 NIH-funded trial results likely will impact global treatment guidelines A major international randomized clinical trial has found that HIV-infected individuals have a considerably lower risk of developing AIDS or other serious illnesses if they start taking antiretroviral drugs sooner, when their CD4+ T-cell count—a key measure of immune…

NIH, South African Medical Research Council award $8 million in HIV, TB grants

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The National Institutes of Health and the South African Medical Research Council (SAMRC) are awarding 31 grants to U.S. and South African scientists to support research targeting HIV/AIDS, tuberculosis and HIV-related co-morbidities and cancers. The awards, which total $8 million in first-year funding, are the first to be issued through the South Africa–U.S. Program for…

NIH Announces Funding for New Technologies for Viral Hepatitis

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The National Institutes of Health (NIH) has issued a funding opportunity announcement (FOA) to encourage small businesses to address viral hepatitis research opportunities delineated in the Action Plan for the Prevention, Care, and Treatment of Viral Hepatitis (Action Plan) [PDF 2MB]. The announcement of a Small Business Innovation Research (SBIR) grant entitled New Technologies for Viral…

Interview with Dr. Anthony Fauci on “Mississippi Baby”

Dr. Fauci

In an important announcement yesterday, Thursday, July 10, the National Institutes of Health (NIH) reported that the child known as the “Mississippi Baby”—an infant seemingly cured of HIV after treatment had been initiated within hours of birth—now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of the…